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How does Infanrix-IPV+Hib work?

Infanrix-IPV+Hib is injected into the muscle, usually in the thigh. Like all vaccines it then stimulates the body’s own systems to produce immunity. Infanrix-IPV+Hib protects against:


  • Diphtheria mainly affects the airways and sometimes the skin
  • Generally the airways become inflamed (swollen) causing serious breathing difficulties and sometimes suffocation
  • Diphtheria is caused by bacteria called Corynebacterium diphtheriae which release a toxin (poison) which can cause nerve damage, heart problems and even death


  • The bacteria that cause tetanus enter the body through cuts, scratches or wounds in the skin
  • Wounds that are especially prone to infection are burns, open wounds that are associated with broken bones, deep wounds or wounds contaminated with soil, dust, manure/dung or wood splinters
  • The bacteria release a toxin (poison), which can cause muscle stiffness, painful muscle spasms, fits and even death
  • The muscle spasms can be strong enough to cause fractures of the spine

Whooping cough

  • Whooping cough is a highly infectious illness
  • The disease affects the airways causing severe spells of coughing that may lead to problems with breathing
  • The coughing is often accompanied by a “whooping” sound, hence the common name “whooping cough”
  • The cough may last for 1-2 months or longer
  • The bacteria that cause whooping cough can also cause ear infections, bronchitis which may last a long time, pneumonia, fits, brain damage and even death


  • Poliomyelitis, sometimes called ‘polio’ is a viral infection that can have variable effects
  • Often it causes only a mild illness but sometimes it can be very serious and cause permanent damage or even death
  • In its severest form, polio infection causes paralysis of the muscles (muscles cannot move), including those muscles needed for breathing and walking
  • The limbs affected by the disease may be painfully deformed


Hib bacteria can cause a range of diseases:

  • Respiratory infections
  • Meningitis: infection of areas of the brain and spinal cord
  • Bacteraemia: bacteria in the blood
  • Pericarditis: infection of tissue surrounding the heart
  • Cellulitis: skin infection

Infanrix-IPV+Hib will only protect against infections caused by the bacteria and viruses which cause the diseases described above.

Please see the Infanrix-IPV+Hib Patient Information Leaflet (PIL) for more information.


If you experience any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in the package leaflet. You can also report side effects directly via the Yellow Card Scheme at:
By reporting side effects you can help provide more information on the safety of this medicine.

Infanrix-IPV+Hib is a registered trademark of the GlaxoSmithKline Group of Companies

L.S. Last updated: 07 December 2015. UK/VAC/0019/14(1)a