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How does Nucala work

This page is specifically for patients who have been prescribed Nucala. If you are not a patient who has already been prescribed Nucala, please return to the public website.

What does Nucala do?

  • When eosinophils (white blood cells) move from your blood into your lungs, they can cause your airways to become inflamed, increasing the risk of a severe asthma attack
  • Interleukin-5 (IL-5) contributes to the development and survival of eosinophils.
Pathway
  • Nucala blocks IL-5 binding to eosinophils and reduces the number of eosinophils in your blood, leading to less inflammation in your lungs
Pathway 2

Should I continue my existing medication

  • Yes. Nucala is an add-on treatment, which means you should continue to take your other medications as prescribed by your doctor. 
  • It is recommended that all patients with asthma have an asthma action plan. 
  • If you have any questions, please ask your doctor or nurse at your next appointment.

Nucala is a registered trademark of the GlaxoSmithKline group of companies

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard or search for MHRA Yellowcard in the Google Play or Apple App store. Adverse events should also be reported to GlaxoSmithKline on 0800 221 441.