Blenrep▶︎ (belantamab mafodotin)

Frequently asked questions

We understand starting a new treatment can come with a host of questions. We have included a few below - if you have any additional questions, we recommend talking to your cancer care team.

What is a monoclonal antibody?

A monoclonal antibody (mAb) is a protein made in a laboratory that looks and works like an antibody made by your body’s immune system. Antibodies stick to specific proteins on the surface of harmful or abnormal cells and act as a flag for the immune system to destroy them.

What is B-cell maturation antigen (BCMA)?

BCMA is a protein that is found in large amounts on the outside of myeloma cancer cells, but in lower amounts on healthy cells. This makes it a good target for BCMA-targeting drugs, like BLENREP, so that treatments can kill the cancerous multiple myeloma cells.

Why does BLENREP lead to eye-related side effects?

BLENREP can be absorbed by healthy cells in the body, including cells on the outside of the eye, called the cornea, which may lead to changes that can happen with or without symptoms.

How can I tell if my vision is blurred if I am already using prescription glasses?

During your first eye test, your eye care professional will assess your eyesight, including your glasses prescription. Tell your doctor or nurse if your vision is getting worse even when wearing glasses.

Can I continue working during treatment?

Consult your doctor or care team and consider how you may be able to adjust your work as needed, especially if you drive or operate machinery. If you have difficulty reading or seeing screens clearly, discuss these with your care team, who may be able to provide suggestions and support for you.

Can I continue taking other medications?

It is important to tell your doctor about all other medications you are taking before you start BLENREP. If you experience a side effect or another medical issue while receiving BLENREP, talk to your doctor before taking any medication, including over-the-counter medicines or natural remedies or supplements.

Can I still go on holiday during treatment?

Talk to your doctor before booking any holidays to make sure that they don’t overlap with your treatments. Your doctor might change how often you have treatments, which can change your appointment dates.